INTRODUÇÃO: Neuroblastoma is one of the most common neoplasms in childhood, especially in children under 18 months of age. It is a tumor in precursor nerve cells of the sympathetic nervous system. – OBJETIVOS: To survey clinical, epidemiological and survival data of patients treated for neuroblastoma at Hospital Pequeno Príncipe (HPP) in Curitiba, PR between 2000 and 2020. – MATERIAIS E MÉTODO: This was a retrospective observational study based on data from the medical records of patients at the HPP. – RESULTADOS: The study analyzed 90 medical records of patients with neuroblastic tumors; 54.5% were male. At diagnosis, the highest relative frequency was observed in patients younger than 18 months (44.4%) and stage IV (32.3%) according to the International Neuroblastoma Staging System (INSS) classification. The most frequent main complaint was abdominal pain (14.5%), and most of the histology of the lesions was poorly differentiated (25.6%). According to these patients’ treatment and prognostic data, 58.9% of cases did not amplify the MYC-N oncogene, and the primary tumor location was more present in the adrenal glands (46.7%). Most affected had neither early (49%) nor late (54.3%) metastasis. It was also exposed to a higher negative frequency of the tumor in the bone marrow (55.6%); more than half of the patients did not present recurrence (60%), and during the treatment, there was a large portion that underwent surgery for total or partial removal of the tumor (94.5%), and also chemotherapy (63.3%). After treatment, 44.4% of those affected survived the disease. – CONSIDERAÇÕES FINAIS: NB has variable clinical and epidemiological characteristics; however, it is possible to evidence and correlate the data obtained with other populations as the age of diagnosis and the most constant manifestations around this malignant neoplasm.
